Cst foxo3a

WebApr 19, 2024 · The primary antibodies used in this study were AKT (1:1000; total and Ser473, Cell Signaling Technology Inc., Danvers, MA, USA), TOR (1:2000; total and Ser2448, CST), S6K1 (1:2000; total and Thr421/Ser424, CST), FOXO3a (1:3000; total and Ser253, Abcam, Cambridge, MA, USA), MAFBX and MURF-1 (1:4000; Zen … WebNov 15, 2016 · Besides, FoxO3a can trigger apoptosis by promoting the expressions of death receptor ligands in the extrinsic apoptotic pathway, such as Fas ligand 33 and tumor-necrosis-factor-related apoptosis ...

Phosphorylation of FOXO3a on Ser-7 by p38 Promotes Its Nuclear ...

WebSignaling Technology (CST) allows the researcher to specifically inhibit FoxO3a expression using RNA interfer-ence, a method whereby gene expression can be selectively silenced … WebThe FOXO3 and FOXM1 forkhead box transcription factors, functioning downstream of the essential PI3K-Akt, Ras-ERK and JNK/p38MAPK signalling cascades, are crucial for cell proliferation, differentiation, cell survival, senescence, DNA … china flexible led profile customized https://infotecnicanet.com

SignalSilence FoxO3a siRNA I - Cell Signaling Technology

WebHighly specific and rigorously validated in-house, FoxO3a Antibody (CST #9467) is ready to ship. ... Within the family, three members (FoxO1, … WebMonoclonal Antibody for studying FoxO3a. Cited in 446 publications. Validated for WB, IP, IF. Highly specific and rigorously validated in-house, FoxO3a (75D8) Rabbit Monoclonal … WebJul 25, 2024 · FOXO3a is widely implicated in a variety of diseases, particularly in malignancy of breast, liver, colon, prostate, bladder, and nasopharyngeal cancers. … graham clan books

Elucidating the role of the FoxO3a transcription factor in the …

Category:国家自然基金委通报今年首批八起学术不端案件,七起涉“医”_科学 …

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Cst foxo3a

FOXO3 - Wikipedia

WebForkhead box O (FOXO) proteins are a family of transcription factors with four members in mammals, namely FOXO1, FOXO3a, FOXO4, and FOXO6. FOXO factors, originally identified as downstream regulators of the insulin pathway, are known to bind to the promoters of a broad variety of target genes and co … Introduction to FOXO Biology WebMay 21, 2024 · FOXO3a is a member of the FOXO transcription factor family, which plays a pivotal role in maintaining redox balance. Activation of the SIRT1/FOXO3a pathway can inhibit oxidative stress primarily by regulating antioxidant enzymes [ [13], [14], [15] ].

Cst foxo3a

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WebApr 12, 2024 · 国家自然基金委通报今年首批八起学术不端案件,七起涉“医”. 澎湃新闻记者 贾利略. 2024-04-12 08:08 来源:澎湃新闻. 国家自然科学基金委员会官网4月11日的通报还涉及一篇中文期刊论文相关的学术不端案件。. 4月11日,国家自然科学基金委员会官网通报 … WebJan 1, 2012 · Doxorubicn treatment induces p38 MAPK activity and FOXO3a nuclear accumulation in MCF-7 breast carcinoma cell line. A, MCF-7 cells were treated with 1 μmol/liter of doxorubicin for 0, 1, 2, 4, 8, 16, and 24 h. At the indicated time, the cells were collected and analyzed by Western blotting using the antibodies indicated.

WebMonoclonal Antibody for studying FoxO3a. Cited in 455 publications. Validated for WB, IP, IF. Highly specific and rigorously validated in … WebDec 1, 2016 · For example, FoxO3a activates FasL transcription, the ligand for the Fas-dependent cell death pathway or pro-apoptotic Bim gene and initiates apoptosis. FoxO3a also induces the expression of cell cycle progression inhibitors including p27 and CyclinD1, thus stalling the G1/S phase transition . Here, we investigated whether the survival …

Web豆丁网是面向全球的中文社会化阅读分享平台,拥有商业,教育,研究报告,行业资料,学术论文,认证考试,星座,心理学等数亿实用 ... WebDirections for Use: CST recommends transfection with 100 nM FoxO3a siRNA I 48 to 72 hours prior to cell lysis. For transfection procedure, follow protocol provided by the transfection reagent manufacturer. Please feel free to …

WebFox03a Antibody 可检测 Fox03a 总蛋白的外源和内源水平。 该抗体不检测外源表达的家族成员 Fox04 或 Fox01。 该抗体与牛血清(包括 BSA)的变性组分发生反应。 物种反应性: 人, 猴 基于 100% 序列同源性预测发生 …

WebJul 16, 2024 · The differential expressions of IGF-1R, FOXO3A, and BIM in the benign versus malignant prostate tissues supported a negative association between the FOXO3A/BIM axis and IGF-1R expression in human ... graham civil warWebMonoclonal Antibody for studying FoxO3a. Cited in 187 publications. Validated for WB, IP, IHC, IF, F. Highly specific and rigorously validated in-house, FoxO3a (D19A7) Rabbit Monoclonal Antibody (CST #12829) is … graham clarke attorney panama cityWeb(12829) FoxO3a (D19A7) Rabbit mAb Sign in or register to save this reagent to your favourites Supplier Cell Signaling Technology Host Rabbit Type Primary Clonality Recombinant (D19A7F3) Recombinant Yes Conjugate Unconjugated Target Forkhead box protein O3 (Human) UniProt O43524 - FOXO3_HUMAN Gene FOXO3 Modification … graham clarke artistWebApr 22, 2024 · FOXO3a is a key target of AKT, and AKT phosphorylates FOXO3a at Thr32 residues, resulting in a decreased expression of FOXO3a. We then investigated whether … china flexible packaging marketWebFOXO3a is a transcription factor of the FOXO family. The FOXO proteins participate in multiple signaling pathways, and their transcriptional activity is regulated by several post … graham clan crestWebMar 27, 2008 · A number of posttranslational modifications within the forkhead DNA-binding domain regulate FoxO-mediated transcription. We describe the crystal structures of … graham clarke etchingWebFoxO3a (75D8) Rabbit mAb detects exogenous and endogenous levels of total FoxO3a protein. The antibody does not detect the exogenously expressed family members FoxO4 or FoxO1. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification china flexible stainless steel mesh